WASD
Click
E
F
Space
O
P
V
H
X
Move, Jump, or Swim
Break or place blocks
Open inventory or block
Eat/Drink held item
Split items while crafting
Save current game
Pause current game
View advancements
Use telescope
Quit game

To open functional blocks hover your 

cursor over it and press [E]

Press [U] to view your latest autosave

Other settings can be changed with

commands [T]